Textbook of Pharmacology, 2nd Edition
Jagadish Prasad
216 x 280 mm
Year of Publishing
Territorial Rights
Universities Press

Pharmacology is one of the fast-growing branches of medical science. This book deals with both basic information in the subject of Pharmacology as well as advanced aspects and pharmacological approaches for drug treatment of clinical conditions. Latest advancements in pharmacology during the recent past—development of newer drugs for diabetes mellitus (newer insulins, GLP-1 analogs, DPP-4 inhibitors, SGLT-2 inhibitors), anti-TB drugs (bedaquilin), additional generations of cephalosporins, newer antimalignancy drugs  (monoclonal antibodies), and newer anti-HIV drugs (NNRTIs and protease inhibitors) have been incorporated in respective chapters. The book provides comprehensive information about drugs, including the pharmacokinetics, pharmacodynamics, clinical and diagnostic aspects of disease conditions, therapeutic indications, adverse reactions, and drug interactions. This second edition will serve as a basic textbook for undergraduate medical students and those preparing for postgraduate entrance examinations.


  • Simple and comprehensible style 
  • 58 revised and updated chapters dealt under 12 sections 
  • “At a glance” at the beginning of each chapter listing the contents to be dealt with 
  • More than 120 illustrations and chemical structural formulas, 70 schemas, and 160 tables 
  • Important concepts highlighted or given as boxed items 
  • A summary at the end of the chapter as “Recap” 
  • One or more clinical case studies in each chapter 
  • Multiple choice questions with answer key and short-answer questions 
  • Six Appendices dealing with important topics including Prescription Writing and Antibiotic Stewardship Program

Dr P Jagadish Prasad, formerly Professor and Head of the Department of Pharmacology, and Principal Kakatiya Medical College, Warangal, has over forty-three years' experience in teaching and research. He graduated in medicine in 1965 and completed his post-graduation in Pharmacology in 1973 from Guntur Medical College. Since then, he has worked at many government and private medical colleges in  di?erent capacities. He had been an examiner (Medicine and Pharmacy) at different universities across India. He was instrumental in the recruitment of faculty at some medical institutes in the erstwhile state of Andhra Pradesh and was a member of some hospital drug advisory committees. He had been a member of some academic bodies including the Indian Pharmacological Society for three decades. He was the chief coordinator for a WHO program investigating pesticide-related fatalities in Warangal district, Telangana. He also was a consultant for enlisting essential drugs for hospital requirements and for drug research and promotion for a few pharmaceutical companies.

Preface to Second Edition
Preface to First Edition

SECTION I: General Pharmacology
1  Historical Aspects and Introduction, Dosage Forms, and Drug Delivery Systems
2  Pharmacokinetics—Drug Absorption, Distribution, Metabolism, and Elimination
3  Pharmacodynamics—Mechanism of Drug Action, Factors Modifying Drug Effects,       Therapeutic Drug Monitoring, Dose–Response Relationship
4  Adverse Drug Reactions, Drug Interactions, and Drug Assay
5  Drug Usage, Essential Drug Concept, and Drug Development

SECTION 2: Drugs Acting on Autonomic Nervous System
6  General Considerations of Autonomic Nervous System and Neurohumoral Transmission
7  Adrenergic System and Adrenergic Drugs
8  Adrenergic Blocking Drugs
9  Cholinergic System and Cholinergic Drugs
10  Anticholinergic Drugs and Drugs Acting on Autonomic Ganglia

SECTION 3: Drugs Acting on Cardiovascular System
11  General Considerations and Antihypertensive Drugs
12  Ischemic Heart Disease (IHD) and Treatment of Angina Pectoris
13 Drugs for Congestive Heart Failure
14 Drugs Used in Cardiac Arrhythmias

SECTION 4: Drugs Acting on Kidney
15 Diuretics

SECTION 5: Drugs Acting on Central Nervous System
16  Organization and Functioning of Central Nervous System and Central Neurotransmitters, Sedatives, and Hypnotics
17  General Anesthetics, Skeletal Muscle Relaxants, and Local Anesthetics
18  Therapeutic Approaches to Neurodegenerative and Movement Disorders
19 Drug Treatment of Psychotic Disorders
20 Drug Treatment of Epileptic Disorders
21 Opioid Analgesics
22  Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and Drugs for Rheumatoid Arthritis and Gouty Arthritis
23 The Alcohols and Drugs of Abuse

SECTION 6: Autacoids
24  Histamine, H1 Antagonists, 5-Hydroxytryptamine (5-HT), and 5-HT Agonists and Antagonists
25  Ergot Alkaloids, Eicosanoids, and Vasoactive Peptides

SECTION 7: Chemotherapeutic Agents
26  General Considerations of Antibiotics, Sulfonamides, Trimethoprim, Quinolones, and
Urinary Antiseptics and Analgesics
27  Penicillins, Cephalosporins, the Beta-lactam Antibiotics, and Miscellaneous Antibiotics
28 Aminoglycosides
29  Tetracyclines and Chloramphenicol
30  Macrolides, Ketolides, Clindamycin, Streptogramins, Oxazolidinediones, and Other Antibiotic Agents
31  Chemotherapy of Tuberculosis and Leprosy
32  Chemotherapy of Protozoal Infections
33  Antiviral Agents and Anti-HIV Drugs
34  Antifungal Agents
35 Anthelminthic Agents
36 Cancer Chemotherapy

SECTION 8: Endocrine Disorders and Therapeutic Considerations
37  Hypothalamic–Pituitary Hormones
38  Adrenocorticotropic Hormones and Adrenocortical Steroids
39 Thyroid Hormones and Antithyroid Drugs
40 Ovarian Hormones
41  Androgens and Antiandrogens
42 Pancreatic Hormones and Antidiabetic Drugs
43 Drugs Affecting Bone Mineral Metabolism

SECTION 9: The Hemopoietic System
44  Drugs for Iron-Deficiency Anemia
45  Drugs for Megaloblastic Anemia, Hemopoietic Growth Factors
46 Blood Coagulation Disorders

SECTION 10: The Respiratory System
47  Drugs for Respiratory Disorders

SECTION 11: Drugs for Gastrointestinal Disorders
48  Drug Treatment of Acid Peptic Disorders
49 Antiemetic Drugs
50  Drugs for Motility Disorders, Purgatives and Laxatives, Antidiarrheal Agents, and Drug Treatment of Irritable Bowel Syndrome and Inflammatory Bowel Disease

SECTION 12: Miscellaneous Topics
51 Drug Therapy of Hyperlipidemia
52 Intravenous Fluid Therapy
53 Immune Pharmacology
54  Therapeutic Considerations of Toxic Disorders
55 Dermatological Pharmacology
56 Drugs Acting on the Uterus
57  Drug Use During Pregnancy
58 The Vitamins

1 Prescription Writing
2 Antibiotic Stewardship Program (ASP)
3 IAP Immunization Timetable 2016
4  Drug Regulations, Acts, and other Legal Aspects
5  Clinical Laboratory Tests—Reference Values
6  Essential Drugs for Regular and Emergency Use

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